ASE: Functional Stenosis Fairly Common After Mitral Valve Repair
A mean mitral gradient of 5 mm Hg, and a peak gradient of 10 mm Hg at rest, correlated with a mean gradient during exercise of 15 mm Hg, the cutoff for defining mitral stenosis, she reported here at the American Society of Echocardiography.
So for values higher than those, "you might suspect that there might be something going on there that's worthwhile looking at with a stress echo," she said.
Mitral valve repair has become the standard treatment for most cases of severe
Repair tends to reduce the mitral valve area, and there is not much known about the consequences, Chen said. In the experience at her center, she said, some patients who no longer have any regurgitation after repair still have residual exercise intolerance.
To explore what is happening with those patients, Chen and her colleagues assessed exercise performance and
The researchers excluded patients with significant residual regurgitation, greater than mild concomitant valvular disease, a left ventricular ejection fraction of less than 40%, and an inability to exercise.
Testing, including a supine bicycle stress echocardiogram, was completed one to nine years after surgery.
Overall, 34% of patients had residual exercise intolerance, defined as a mean mitral gradient of 15 mm Hg or greater (mitral stenosis) or a right ventricular systolic pressure of 60 mm Hg (pulmonary hypertension) at peak exercise. Five patients had both.
Patients with exercise intolerance had a smaller mitral valve area (1.95 versus 2.31 cm ≤0.0002 for both) -- showing that patients with pulmonary hypertension report feeling worse than other patients.
In future studies, Chen said she hopes to identify intraoperative characteristics associated with residual exercise intolerance, so the outcome can be avoided.
She and her colleagues are focusing on the use of mitral valve rings because patients with exercise intolerance in the current study were more likely to have one used during surgery (56% versus 20%, P MedPage Today provides daily, peer-reviewed medical news articles, written specifically for the clinician.
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Mitral Valve Disease - News
Nearly all (97%) had mitral annuloplasty (66% with a posterior annular band and 31% with a full ring). The researchers excluded patients with significant residual regurgitation; greater than mild concomitant valvular disease; a left ventricular
The Texas-based hospital, which specializes in the diagnosis and treatment of cardiovascular disease, chose the system to assist with valve repair surgery, specifically for tricuspid and mitral valve repair procedures. With xMATRIX technology, the iE33
He and his colleagues looked at baseline plasma SP-D levels in 806 patients with stable angina, prior MI, or aortic-valve or mitral-valve disease and who showed coronary artery disease on angiography performed for assessment of CV risk;
According to the American Heart Association, valve disease most often strikes either the mitral valve, which controls blood flow into the heart, or the aortic valve, which controls blood flow out of the heart. Valvular heart disease causes about 20000
be caused by caffeine consumption, amphetamines ('speed' is the street slang for amphetamines when they are not prescribed by a doctor), an overactive thyroid, abnormal heart rhythms, and other heart abnormalities (such as mitral valve prolapse).
Novel Percutaneous Dual Catheter System for Mitral Valve Leaflet ...
Myxomatous mitral valve disease is a form of mitral valve prolapse that leads to regurgitation and cardiac dysfunction, especially in older men. Its severity necessitates surgical repair or replacement, either of which is expensive and requires substantial recovery time. Thus, there is a strong clinical need for percutaneous treatment for patients with myxomatous mitral valve disease as a alternative to open-chest surgery.
A dual-purpose catheter system that accomplishes both valvular anchorage and ablation; Unique catheter guided cryo-ablation for leaflet adherence; Applies well controlled radiofrequency energy to induce intrinsic valve stiffness; Reduces mitral valve regurgitation and improves cardiac function; Reduces patient recovery and hospitalization time; Less procedural related side effects i.e. endocarditis; Technology could be very applicable in other intricate cardiovascular procedures Researchers at The University of Alabama at Birmingham (UAB) have developed a novel percutaneous dual catheter device that enables precise non-surgical attachment and delivery of radiofrequent energy to a moving defective mitral valve leaflet. This technology has been shown to stimulate collagen coagulation for the treatment of mitral valve prolapse where collagen disruption is the hallmark pathology. According to the American Heart Association 2003 report, various forms of mitral valve disease contributed to or were directly related to approximately 9,000 deaths and resulted in 43,000 inpatient procedures. Along with preserving the left ventricular function, we foresee this technology greatly lowering the mortality rate and improving patient prognosis with fewer side effects as compared to open-chest heart surgery. This innovative product is highly appealing to both physician and patients with myxomatous mitral valve disease. Alfred R Berkeley, Chairman, Pipeline Financial Group, Inc., Former President and Vice Chairman, Nasdaq Stock Market, Inc."Our economy is inextricably intertwined with university innovations. Unfortunately, our country’s short-term outlook often interferes with the long-term possibilities of university research and collaborations with industry and entrepreneurs..." read more...
Mitral Valve Disease - Bookshelf
Mitral valve disease, diagnosis and treatment
Mitral valve disease
Mitral valve disease
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